Therapeutic Plasma Exchange (TPE), also known as plasmapheresis, is a treatment we use to support patients with conditions like thrombocytopenic purpura (TTP) or hyperviscosity. During TPE, a portion of your blood is drawn and the plasma is separated. This plasma is then replaced with either healthy donor plasma or a saline and albumin solution, and the treated blood is returned to your body through an IV.

We often begin TPE treatments while you're in the hospital and continue them on an outpatient basis. Before starting, you'll need a special central venous catheter placed, which will stay in place until your treatment course is complete.

Each session typically lasts between one and four hours, and the number of treatments depends on your specific condition and response to therapy.