levothyroxine (oral/injection)
Pronunciation: LEE voe thye ROX een
Synthroid
137 mcg (0.137 mg), round, blue, imprinted with SYNTHROID, 137

Synthroid
25 mcg (0.025 mg), round, orange, imprinted with SYNTHROID, 25

Synthroid
50 mcg (0.05 mg), round, white, imprinted with SYNTHROID, 50

Synthroid
75 mcg (0.075 mg), round, lavender, imprinted with SYNTHROID, 75

Synthroid
88 mcg (0.088 mg), round, green, imprinted with SYNTHROID, 88

Synthroid
100 mcg (0.1 mg), round, yellow, imprinted with SYNTHROID, 100

Synthroid
125 mcg (0.125 mg), round, beige, imprinted with SYNTHROID, 125

Synthroid
150 mcg (0.15 mg), round, blue, imprinted with SYNTHROID, 150

Synthroid
175 mcg (0.175 mg), round, purple, imprinted with SYNTHROID, 175

Synthroid
200 mcg (0.2 mg), round, pink, imprinted with SYNTHROID, 200

Synthroid
300 mcg (0.3 mg), round, green, imprinted with SYNTHROID, 300

Synthroid
112 mcg (0.112 mg), round, pink, imprinted with SYNTHROID, 112

Levothyroxine Sodium
25 mcg (0.025 mg), capsule, orange, imprinted with M, L 4

Levothyroxine Sodium
50 mcg (0.05 mg), capsule, white, imprinted with M, L 5

Levothyroxine Sodium
75 mcg (0.075 mg), oval, purple, imprinted with M, L 6

Levothyroxine Sodium
88 mcg (0.088 mg), capsule, olive, imprinted with M, L 7

Levothyroxine Sodium
100 mcg (0.1 mg), oval, yellow, imprinted with M, L 8

Levothyroxine Sodium
112 mcg (0.112 mg), oval, pink, imprinted with M, L 9

Levothyroxine Sodium
125 mcg (0.125 mg), capsule, gray, imprinted with M, L 10

Levothyroxine Sodium
150 mcg (0.15 mg), capsule, blue, imprinted with M, L 11

Levothyroxine Sodium
175 mcg (0.175 mg), oval, lilac, imprinted with M, L 12

Levothyroxine Sodium
200 mcg (0.2 mg), oblong, pink, imprinted with M, L 13

Levothyroxine Sodium
300 mcg (0.3 mg), oblong, dark green, imprinted with M, L 14

Levothyroxine Sodium
137 mcg (0.137 mg), oblong, blue, imprinted with M, L 15

Levothyroxine Sodium
25 mcg (0.025 mg), round, orange, imprinted with JSP, 513

Levothyroxine Sodium
50 mcg (0.05 mg), round, white, imprinted with JSP, 514

Levothyroxine Sodium
75 mcg (0.075 mg), round, purple, imprinted with JSP, 515

Levothyroxine Sodium
88 mcg (0.088 mg), round, green, imprinted with JSP, 561

Levothyroxine Sodium
100 mcg (0.1 mg), round, yellow, imprinted with JSP, 516

Levothyroxine Sodium
112 mcg (0.112 mg), round, pink, imprinted with JSP 562

Levothyroxine Sodium
125 mcg (0.125 mg), round, beige, imprinted with JSP, 519

Levothyroxine Sodium
150 mcg (0.15 mg), round, blue, imprinted with JSP, 520

Levothyroxine Sodium
175 mcg (0.175 mg), round, lavender, imprinted with JSP, 563

Levothyroxine Sodium
200 mcg (0.2 mg), round, pink, imprinted with JSP, 522

Levothyroxine Sodium
300 mcg (0.3 mg), round, green, imprinted with JSP 523

Levothyroxine Sodium
137 mcg (0.137 mg), round, blue, imprinted with JSP, 564

Levothyroxine Sodium
25 mcg (0.025 mg), capsule, orange, imprinted with 25, GG 331

Levothyroxine Sodium
50 mcg (0.05 mg), oblong, white, imprinted with 50, GG 332

Levothyroxine Sodium
75 mcg (0.075 mg), oblong, lavender, imprinted with 75, GG 333

Levothyroxine Sodium
88 mcg (0.088 mg), capsule, green, imprinted with 88, GG 334

Levothyroxine Sodium
100 mcg (0.1 mg), oblong, yellow, imprinted with 100, GG 335

Levothyroxine Sodium
112 mcg (0.112 mg), capsule, red, imprinted with 112, GG 336

Levothyroxine Sodium
125 mcg (0.125 mg), oblong, beige, imprinted with GG 337, 125

Levothyroxine Sodium
150 mcg (0.15 mg), capsule, blue, imprinted with 150, GG 338

Levothyroxine Sodium
175 mcg (0.175 mg), capsule, purple, imprinted with 175, GG 339

Levothyroxine Sodium
200 mcg (0.2 mg), oblong, pink, imprinted with 200, GG 340

Levothyroxine Sodium
300 mcg (0.3 mg), oblong, green, imprinted with 300, GG 341

Levothyroxine Sodium
137 mcg (0.137 mg), capsule, green, imprinted with 137, GG 330

Levoxyl
88 mcg (0.088 mg), oval, green, imprinted with LEVOXYL, dp 88

Levoxyl
100 mcg (0.1 mg), oval, yellow, imprinted with LEVOXYL, dp 100

Levoxyl
150 mcg (0.15 mg), oval, blue, imprinted with LEVOXYL, dp 150

Levoxyl
175 mcg (0.175 mg), oval, turquoise, imprinted with LEVOXYL, dp 175

Levoxyl
200 mcg (0.2 mg), oval, pink, imprinted with LEVOXYL, dp 200

Synthroid
175 mcg (0.175 mg), round, purple, imprinted with SYNTHROID, 175

Synthroid
25 mcg (0.025 mg), round, orange, imprinted with SYNTHROID, 25

Synthroid
50 mcg (0.05 mg), round, white, imprinted with SYNTHROID, 50

Synthroid
75 mcg (0.075 mg), round, lavender, imprinted with SYNTHROID, 75

Synthroid
88 mcg (0.088 mg), round, green, imprinted with SYNTHROID, 88

Synthroid
100 mcg (0.1 mg), round, yellow, imprinted with SYNTHROID, 100

Synthroid
125 mcg (0.125 mg), round, beige, imprinted with SYNTHROID, 125

Synthroid
150 mcg (0.15 mg), round, blue, imprinted with SYNTHROID, 150

Synthroid
200 mcg (0.2 mg), round, pink, imprinted with SYNTHROID, 200

Synthroid
112 mcg (0.112 mg), round, pink, imprinted with SYNTHROID, 112

Euthyrox
100 mcg (0.1 mg), round, yellow, imprinted with 100 M

Levothroid
25 mcg (0.025 mg), round, orange, imprinted with LOGO, 25

Levothroid
50 mcg (0.05 mg), oblong, white, imprinted with T 4, 50

Levothroid
50 mcg (0.05 mg), round, white, imprinted with LOGO, 50

Levothroid
75 mcg (0.075 mg), oblong, lavender, imprinted with T 4, 75

Levothroid
75 mcg (0.075 mg), round, gray, imprinted with LOGO, 75

Levothroid
88 mcg (0.088 mg), oblong, green, imprinted with T 4, 88

Levothroid
88 mcg (0.088 mg), round, green, imprinted with LOGO, 88

Levothroid
100 mcg (0.1 mg), oblong, yellow, imprinted with T 4, 100

Levothroid
100 mcg (0.1 mg), round, yellow, imprinted with LOGO, 100

Levothroid
112 mcg (0.112 mg), oblong, pink, imprinted with T 4, 112

Levothroid
112 mcg (0.112 mg), round, pink, imprinted with LOGO, 112

Levothroid
125 mcg (0.125 mg), oblong, brown, imprinted with T4, 125

Levothroid
125 mcg (0.125 mg), round, purple, imprinted with LOGO, 125

Levothroid
137 mcg (0.137 mg), round, blue, imprinted with LOGO, 137

Levothroid
150 mcg (0.15 mg), oval, blue, imprinted with T 4, 150

Levothroid
150 mcg (0.15 mg), round, blue, imprinted with LOGO, 150

Levothroid
175 mcg (0.175 mg), oblong, lavender, imprinted with T 4, 175

Levothroid
175 mcg (0.175 mg), round, turquoise, imprinted with LOGO, 175

Levothroid
200 mcg (0.2 mg), oblong, pink, imprinted with T 4, 200

Levothroid
200 mcg (0.2 mg), round, pink, imprinted with LOGO, 200

Levothroid
300 mcg (0.3 mg), oblong, green, imprinted with T 4, 300

Levothroid
300 mcg (0.3 mg), round, green, imprinted with LOGO, 300

Levothyroxine Sodium
25 mcg (0.025 mg), oblong, peach, imprinted with M, L 4

Levothyroxine Sodium
50 mcg (0.05 mg), oblong, white, imprinted with M, L 5

Levothyroxine Sodium
50 mcg (0.05 mg), round, white, imprinted with 3912 V

Levothyroxine Sodium
75 mcg (0.075 mg), oblong, gray, imprinted with M, L 6

Levothyroxine Sodium
88 mcg (0.088 mg), oblong, green, imprinted with M, L 7

Levothyroxine Sodium
100 mcg (0.1 mg), oblong, yellow, imprinted with M, L 8

Levothyroxine Sodium
100 mcg (0.1 mg), round, yellow, imprinted with 3914 V

Levothyroxine Sodium
125 mcg (0.125 mg), oblong, beige, imprinted with M, L 10

Levothyroxine Sodium
125 mcg (0.125 mg), round, peach, imprinted with 3919 V

Levothyroxine Sodium
150 mcg (0.15 mg), capsule, blue, imprinted with M, L 11

Levothyroxine Sodium
150 mcg (0.15 mg), round, blue, imprinted with 3915 V

Levothyroxine Sodium
175 mcg (0.175 mg), oblong, lavender, imprinted with M, L 12

Levothyroxine Sodium
200 mcg (0.2 mg), oblong, red, imprinted with M, L 13

Levothyroxine Sodium
200 mcg (0.2 mg), round, pink, imprinted with 3915 V

Levothyroxine Sodium
300 mcg (0.3 mg), oblong, dark green, imprinted with M, L 14

Levoxyl
25 mcg (0.025 mg), peanut, orange, imprinted with LEVOXYL, dp 25

Levoxyl
50 mcg (0.05 mg), peanut, white, imprinted with LEVOXYL, dp 59, dp 50

Levoxyl
75 mcg (0.075 mg), oval, purple, imprinted with LEVOXYL, dp 75

Levoxyl
88 mcg (0.088 mg), oval, green, imprinted with LEVOXYL, dp 88

Levoxyl
150 mcg (0.15 mg), oval, blue, imprinted with LEVOXYL, dp 150

Levoxyl
175 mcg (0.175 mg), oval, turquoise, imprinted with LEVOXYL, dp 175

Levoxyl
300 mcg (0.3 mg), oval, green, imprinted with LEVOXYL, dp 300

Levoxyl
100 mcg (0.1 mg), oval, yellow, imprinted with LEVOXYL, dp 100

Levoxyl
112 mcg (0.112 mg), oval, pink, imprinted with LEVOXYL, dp 112

Levoxyl
125 mcg (0.125 mg), oval, brown, imprinted with LEVOXYL, dp 125

Levoxyl
137 mcg (0.137 mg), oval, blue, imprinted with LEVOXYL, dp 137

Levoxyl
200 mcg (0.2 mg), oval, pink, imprinted with LEVOXYL, dp 200

Synthroid
25 mcg (0.025 mg), round, orange, imprinted with SYNTHROID, 25

Synthroid
25 mcg (0.025 mg), round, orange, imprinted with FLINT, 25

Synthroid
50 mcg (0.05 mg), round, white, imprinted with SYNTHROID, 50

Synthroid
50 mcg (0.05 mg), round, white, imprinted with FLINT, 50

Synthroid
75 mcg (0.075 mg), round, lavender, imprinted with SYNTHROID, 75

Synthroid
75 mcg (0.075 mg), round, lavender, imprinted with FLINT, 75

Synthroid
88 mcg (0.088 mg), round, green, imprinted with SYNTHROID, 88

Synthroid
88 mcg (0.088 mg), round, green, imprinted with FLINT, 88

Synthroid
100 mcg (0.1 mg), round, yellow, imprinted with SYNTHROID, 100

Synthroid
100 mcg (0.1 mg), round, yellow, imprinted with FLINT, 100

Synthroid
112 mcg (0.112 mg), round, pink, imprinted with SYNTHROID, 112

Synthroid
112 mcg (0.112 mg), round, pink, imprinted with FLINT, 112

Synthroid
125 mcg (0.125 mg), round, beige, imprinted with SYNTHROID, 125

Synthroid
125 mcg (0.125 mg), round, beige, imprinted with FLINT, 125

Synthroid
137 mcg (0.137 mg), round, blue, imprinted with SYNTHROID, 137

Synthroid
150 mcg (0.15 mg), round, blue, imprinted with SYNTHROID, 150

Synthroid
150 mcg (0.15 mg), round, blue, imprinted with FLINT, 150

Synthroid
175 mcg (0.175 mg), round, purple, imprinted with SYNTHROID, 175

Synthroid
175 mcg (0.175 mg), round, purple, imprinted with FLINT, 175

Synthroid
200 mcg (0.2 mg), round, pink, imprinted with SYNTHROID, 200

Synthroid
200 mcg (0.2 mg), round, pink, imprinted with FLINT, 200

Synthroid
300 mcg (0.3 mg), round, green, imprinted with SYNTHROID, 300

Unithroid
25 mcg (0.025 mg), round, orange, imprinted with JSP, 513

Unithroid
88 mcg (0.088 mg), round, green, imprinted with JSP, 561

Levothyroxine Sodium
100 mcg (0.1 mg), round, yellow, imprinted with JSP, 516

Unithroid
112 mcg (0.112 mg), round, pink, imprinted with JSP, 562

Levothyroxine Sodium
150 mcg (0.15 mg), round, blue, imprinted with JSP, 520

Unithroid
175 mcg (0.175 mg), round, lavender, imprinted with JSP, 563

Unithroid
300 mcg (0.3 mg), round, green, imprinted with JSP, 523

What is the most important information I should know about levothyroxine?
You may not be able to use levothyroxine if you have certain medical conditions. Tell your doctor if you have an untreated or uncontrolled adrenal gland disorder, a thyroid disorder called thyrotoxicosis, or if you have any recent or current symptoms of a heart attack.
Levothyroxine should not be used to treat obesity or weight problems.
What is levothyroxine?
Levothyroxine is used to treat hypothyroidism (low thyroid hormone). Levothyroxine is given when your thyroid does not produce enough of this hormone on its own.
Levothyroxine is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer.
There are many brands and forms of levothyroxine available. Not all brands are listed on this leaflet.
Levothyroxine may also be used for purposes not listed in this medication guide.
What should I discuss with my healthcare provider before using levothyroxine?
Levothyroxine should not be used to treat obesity or weight problems. Dangerous side effects or death can occur from the misuse of levothyroxine, especially if you are taking any other weight-loss medications or appetite suppressants.
Since thyroid hormone occurs naturally in the body, almost anyone can use levothyroxine. However, you may not be able to use this medicine if you have certain medical conditions. Tell your doctor if you have:
- an untreated or uncontrolled adrenal gland disorder;
- a thyroid disorder called thyrotoxicosis; or
- symptoms of a heart attack (chest pain or heavy feeling, pain spreading to the jaw or shoulder, nausea, sweating, general ill feeling).
Tell your doctor if you have ever had:
- a thyroid nodule;
- heart disease, a blood clot, or a blood-clotting disorder;
- diabetes (insulin or oral diabetes medication doses may need to be changed when you start using levothyroxine);
- kidney disease;
- anemia (lack of red blood cells);
- osteoporosis, or low bone mineral density;
- problems with your pituitary gland; or
- any food or drug allergies.
Tell your doctor if you have recently received radiation therapy with iodine (such as I-131).
If you become pregnant while using levothyroxine, do not stop using the medicine without your doctor's advice. Having low thyroid hormone levels during pregnancy could harm both mother and baby. Your dose needs may be different during pregnancy.
Tell your doctor if you are breastfeeding. Your dose needs may be different while you are nursing.
Do not give this medicine to a child without medical advice. Tirosint is not approved for use by anyone younger than 6 years old.
How should I use levothyroxine?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Levothyroxine oral is taken by mouth. Levothyroxine injection is given as an infusion into a vein. Levothyroxine is usually given by injection only if you are unable to take the medicine by mouth.
Levothyroxine oral works best if you take it on an empty stomach, 30 to 60 minutes before breakfast. Follow your doctor's dosing instructions and try to take the medicine at the same time each day.
Swallow the tablet or capsule whole, with a full glass (8 ounces) of water. The levothyroxine tablet may dissolve very quickly and could swell in your throat.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Levothyroxine doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight.
It may take several weeks before your body starts to respond to levothyroxine. Keep using this medicine even if you feel well. You may need to use levothyroxine for the rest of your life.
You may need frequent medical tests. Tell any doctor, dentist, or surgeon who treats you that you are using levothyroxine.
Store at room temperature away from moisture and heat. Use Tirosint-Sol within 3 months after opening the pouch.
Do not share this medicine with another person, even if they have the same symptoms you have.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include headache, leg cramps, tremors, feeling nervous or irritable, chest pain, shortness of breath, and fast or pounding heartbeats.
What should I avoid while using levothyroxine?
Avoid the following food products, which can make your body absorb less levothyroxine: grapefruit juice, infant soy formula, soybean flour, cotton seed meal, walnuts, and high-fiber foods.
What are the possible side effects of levothyroxine?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- fast or irregular heartbeats;
- chest pain, pain spreading to your jaw or shoulder;
- shortness of breath;
- fever, hot flashes, sweating;
- tremors, or if you feel unusually cold;
- weakness, tiredness, sleep problems (insomnia);
- memory problems, feeling depressed or irritable;
- headache, leg cramps, muscle aches;
- feeling nervous or irritable;
- dryness of your skin or hair, hair loss;
- irregular menstrual periods; or
- vomiting, diarrhea, appetite changes, weight changes.
Certain side effects may be more likely in older adults.
Common side effects may include:
- chest pain, irregular heartbeats;
- shortness of breath;
- headache, leg cramps, muscle pain or weakness;
- tremors, feeling nervous or irritable, trouble sleeping;
- increased appetite;
- feeling hot;
- weight loss;
- changes in your menstrual periods;
- diarrhea; or
- skin rash, partial hair loss.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect levothyroxine?
Many other medicines can be affected by your thyroid hormone levels. Certain other medicines may also increase or decrease the effects of levothyroxine.
If you use any of the following drugs, avoid taking them within 4 hours before or 4 hours after you use levothyroxine:
- calcium carbonate (Alka-Mints, Caltrate, Os-Cal, Oyster Shell Calcium, Rolaids Soft Chew, Tums, and others);
- cholestyramine, colesevelam, colestipol;
- ferrous sulfate iron supplement;
- sucralfate;
- sodium polystyrene sulfonate (Kalexate, Kayexalate, Kionex);
- stomach acid reducers --esomeprazole, lansoprazole, omeprazole, rabeprazole, Nexium, Prilosec, Prevacid, Protonix, Zegerid, and others; or
- antacids that contain aluminum or magnesium --Gaviscon, Maalox, Milk of Magnesia, Mintox, Mylanta, Pepcid Complete, and others.
Many drugs can affect levothyroxine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information?
Your doctor or pharmacist can provide more information about levothyroxine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2022 Cerner Multum, Inc. Version: 16.01. Revision date: 4/20/2022.